Tupelo Data Room

medical practice for Sale in New York

Similar businesses sell at 0.9x to 4.7x SDE. Compare live listings and connect with sellers.

Virtual Mental Health Practice – Serving High-Performing Professionals photo
Medical Practices
+1

Virtual Mental Health Practice – Serving High-Performing Professionals

New York County, NY, US

This established virtual mental health practice specializes in providing high-quality, evidence-based therapy services to high-performing professionals and adults navigating stress, anxiety, burnout, and major life transitions. The business has developed a strong niche within a growing segment of the behavioral health market, focusing on individuals who are outwardly successful but seeking deeper emotional support and long-term personal development. Operating through a fully virtual model, the practice delivers individual psychotherapy services using proven clinical approaches, including cognitive-behavioral and insight-oriented therapies. Clients are supported in building self-awareness, resilience, and practical coping strategies to improve both personal well-being and professional performance. The practice’s positioning at the intersection of mental health and high performance differentiates it from traditional therapy providers and has contributed to strong client engagement and retention. The business primarily serves a demographic of professionals in demanding industries such as finance, technology, consulting, and healthcare, along with multicultural and first-generation individuals. Clients typically present with high-functioning anxiety, burnout, identity-related challenges, and relationship concerns. The practice maintains a mix of long-term private-pay clients and shorter-term employer-sponsored engagements, creating both recurring revenue and a steady flow of new client introductions. Revenue is generated through a hybrid model that includes private-pay sessions and employer-sponsored programs. The business benefits from a premium pricing structure, with private-pay sessions generating higher revenue per visit, while employer partnerships provide additional volume and client acquisition channels. Payments are collected at the time of service, minimizing accounts receivable risk and supporting strong cash flow. Financial performance has been solid, with annual revenue approaching $700,000 and adjusted earnings exceeding $350,000, reflecting the efficiency of the asset-light, virtual operating model. The business has demonstrated the ability to scale revenue with minimal incremental overhead, supported by a flexible clinician staffing structure. Operations are streamlined and supported by a small team of licensed clinicians operating within a structured yet flexible framework. The practice utilizes modern, HIPAA-compliant systems for scheduling, documentation, billing, and telehealth delivery, allowing for efficient day-to-day management. With no physical office requirements and minimal fixed costs, the business offers strong margins and operational simplicity. The practice has built a strong digital presence, generating consistent inbound demand through organic search, online visibility, and word-of-mouth referrals. Its established brand within a clearly defined niche contributes to ongoing client acquisition without heavy reliance on paid marketing. Additionally, the business has untapped capacity, as current clinician utilization is not fully maximized, presenting an immediate opportunity to increase revenue through improved scheduling and additional hires. This opportunity is ideal for a licensed clinician, group practice owner, or strategic buyer seeking a scalable, high-margin platform in the rapidly growing mental health sector. The business offers a strong foundation, differentiated positioning, and meaningful potential for expansion in a market with sustained demand.

$1,200,000
$689,539Revenue
-Cash Flow
Very Profitable Midtown East Primary Care & Internal Medicine Practice photo
Medical Practices

Very Profitable Midtown East Primary Care & Internal Medicine Practice

New York, NY, US

Exceptional opportunity to acquire a highly profitable primary care and internal medicine practice in one of Manhattan's most desirable medical and professional corridors. Founded in 2002 and operating from its current Midtown East location since 2017, the practice serves an estimated 6,000 loyal patients and benefits from a dense, affluent, year-round market near Grand Central, Turtle Bay, the United Nations, major employers, residential towers, and working professionals. The practice provides comprehensive adult primary care, preventive medicine, annual physicals, vaccinations, chronic disease management, acute care, weight management, asthma and respiratory care, and related internal medicine services. It also offers a broad menu of onsite diagnostics, including EKG/ECG, audiometry, rapid flu and strep testing, PPD/Mantoux testing, peak flow, tympanometry, vital signs, and visual acuity testing. Additional offsite and ancillary services coordinated through the practice include blood testing, echocardiograms, stress testing, Holter monitoring, allergy testing, STD/HIV screening, TB testing, radiology referrals, GeneSight DNA testing, and remote patient monitoring. This is a rare chance to acquire a profitable, reputation-driven medical practice with strong brand equity, deep patient loyalty, and diversified payer relationships. The practice has an exceptional public review profile, including thousands of patient reviews and a high overall rating, helping it stand out in a competitive New York primary care market. It participates with 25+ payer contracts, including major commercial plans, and generates patients through long-standing insurance network participation, referrals, convenient Midtown access, and online appointment functionality. The website supports appointment scheduling, patient forms, prescription refill requests, referrals, online payments, and patient feedback. Financial performance is strong and stable. Net revenue was approximately $1.69 million in 2025, with approximately $620,799 of adjusted EBITDA after normalizing for a market-rate replacement physician/operator. Gross margins are approximately 92% to 93%, reflecting the highly service-oriented nature of the practice. The practice operates from leased office space. The practice is year-round, with weekday operations and limited Saturday access. The buyer should plan for physician licensure, payer credentialing, malpractice coverage, medical records and PHI compliance, DEA/regulatory requirements where applicable, and lease renewal/assignment considerations. The seller is retiring and is willing to support a thoughtful transition for up to six months, including introductions to patients, staff, payers, and referral sources, and will sign customary non-compete/non-solicit protections. The current operation is supported by staff handling billing, reception, and administration, with systems including PatientFusion scheduling, EZClaim billing, digital EMR components, and multiple payment channels. Meaningful upside exists for a buyer with healthcare operating experience. Growth opportunities include expanded digital marketing, added physician or mid-level provider capacity, extended scheduling, revenue-cycle optimization, improved systems and documentation, enhanced patient communication, ancillary service expansion, chronic care management, concierge or membership offerings, and remote patient monitoring. Ideal buyers include a New York-licensed physician, physician group, multi-site primary care platform, or MSO-backed buyer seeking a profitable foothold in a premier Manhattan market. Detailed financial statements, tax returns, payer information, lease materials, and transition details are available to qualified buyers after execution of a confidentiality agreement.

$2,800,000
$1,693,202Revenue
-Cash Flow
Established Integrative Medicine & Internal Medicine Clinic + Property photo
Medical Practices

Established Integrative Medicine & Internal Medicine Clinic + Property

Brooklyn, Kings County, NY, US

Exceptional opportunity to acquire a well-established Integrative & Internal Medicine practice with over 23 years of successful operation and an outstanding reputation in the community. This thriving medical practice offers a rare combination of long-term stability, strong patient retention, and significant growth potential for physicians, medical groups, or investors looking to enter or expand within the healthcare industry. The practice includes an impressive database of approximately 33,000 patients within the EMR/medical portal system, creating an incredible foundation for continued patient care, recurring revenue, and future expansion opportunities. The office has built a loyal patient base over more than two decades by providing high-quality internal and integrative medical care in a professional and patient-focused environment. This is a turnkey operation with established systems, experienced staff, strong community presence, and streamlined day-to-day operations already in place. The practice is ideal for an Internal Medicine physician looking to step into an established patient base, an Integrative or Functional Medicine doctor seeking immediate growth, a medical group looking to expand in the area, or an investor interested in owning a profitable healthcare business while hiring or retaining physicians to operate the practice. In addition to the practice, there is also a separate sale opportunity for the office co-op property, adding long-term real estate value and investment potential. This is a unique opportunity to acquire a respected medical practice with an extensive patient database, strong community presence, and a long-standing history in a growing healthcare market. Serious inquiries only.

$480,000
$721,178Revenue
$414,240Cash Flow
Profitable Chronic Care & Remote Patient Monitoring Business photo
Medical Practices
+1

Profitable Chronic Care & Remote Patient Monitoring Business

NY, US

Business Overview: This New York healthcare services company is just what the doctor ordered — literally! It specializes in chronic care management (CCM) and remote patient monitoring (RPM), partnering with medical practices to keep patients healthier while boosting doctors’ revenue. The company’s turnkey services handle the heavy lifting of routine patient follow-ups and health tracking, alleviating administrative burdens so physicians can focus on care. It’s like having a dedicated virtual care team that never sleeps, ensuring patients stay engaged and on track between office visits. The result? Improved patient outcomes, happier doctors, and a healthy bottom line for this business. Key Highlights: Steady Profits: Generates approximately $300,000 in annual gross revenue with about $108,000 net profit – a healthy margin in a growing industry. Established Client Base: Contracts in place with 11 doctors (and counting) across the New York area. The service model boosts physicians’ practice income, making it a win-win partnership and paving the way for easy expansion to more providers. High-Demand Services: Chronic care management and remote patient monitoring are booming fields thanks to the push for better chronic illness care and telehealth solutions. This company’s personalized approach keeps patients compliant and cared for, which translates to recurring revenue through monthly care plans and monitoring contracts. Turnkey Operation: Based in Brooklyn (Kings County) with an existing office infrastructure. All processes, software, and trained support staff (e.g. medical assistants) are in place to seamlessly continue operations. Minimal owner involvement is needed in day-to-day work – perfect for an investor or a healthcare professional looking to step in and scale. Growth Potential: Virtually unlimited upside by onboarding additional physician practices or expanding services (e.g. other telehealth offerings or additional chronic conditions). The template for success is already proven with current clients, so growing the client base can significantly increase revenue and profit. Reason for Selling: The current owner is pursuing other business ventures. This creates an opportunity for you to acquire a proven, mission-driven healthcare business without starting from scratch. With an established revenue stream, client contracts, and a positive impact on patient health, this business is primed for a new owner to take it to the next level. This is a rare find in the healthcare services sector – a business that makes a difference and makes money. If you’re looking to enter the telehealth/medical services space or expand your existing healthcare portfolio, this company is a perfect fit. Don’t miss out on this “healthy” investment opportunity – it’s truly the cure for the common business!

$499,000
$300,000Revenue
$108,000Cash Flow
Accredited Therapeutic Education Center for Sale photo
Schools
+2

Accredited Therapeutic Education Center for Sale

College Point, Queens County, NY, US

A rare opportunity to acquire a highly respected and fully accredited therapeutic education center with strong enrollment growth and an established reputation for excellence. In 2025, the school served 120 students with annual tuition of approximately $27,195 per student. Due to increasing demand and the addition of new classes, enrollment has grown to 189 students in 2026, with annual tuition of approximately $30,195 per student. As a result, projected 2026 revenue is expected to reach approximately $4.5 million, representing nearly 50% growth year over year. Key Highlights: 189 enrolled students for 2026 Projected annual revenue of approximately $4.5 million Nearly 50% year-over-year growth Financial aid programs available to qualified students Fully licensed and accredited institution Accredited by the Middle States Association Approved and regulated by the New York City Department of Education Nursing school programs and educational services Established quality control systems and compliance standards Experienced staff and strong community reputation This turnkey opportunity is ideal for educational organizations, healthcare operators, strategic buyers, or investors seeking a growing institution with strong demand, established credentials, and significant future expansion potential. Additional information will be provided to qualified buyers upon execution of a Non-Disclosure Agreement (NDA).

$6,500,000
$2,505,296Revenue
$404,355Cash Flow
Turnkey Multi-Location Physical Therapy & Chiropractic Platform photo
Medical Practices
+1

Turnkey Multi-Location Physical Therapy & Chiropractic Platform

Nassau County, NY, US

The Opportunity AcquiTrust Advisors is pleased to exclusively present a long-established Physical Therapy & Chiropractic practice that has been serving the Long Island community for over one decade with 2 locations. This is a rare opportunity to acquire a mature, reputable healthcare business with proven systems, strong referral networks, and consistent financial performance. Unlike many healthcare listings, this practice is not dependent on a single provider and is not a startup or turnaround. It is a stable, cash-flowing operation with infrastructure already in place. Why This Business Stands Out: In business for 10+ years with deep community roots Consistent revenue and strong profitability from 2 locations Exceptional margins for a healthcare practice Diversified payor and referral mix Experienced clinical and administrative staff in place Well-established brand with repeat and referral-driven patient flow The business generated approximately $1.15MM in revenue and ~$426K in net income in 2024, continuing a strong historical trend. Through September 2025, revenue and profitability remain solid, demonstrating ongoing momentum and stability. Owner Transition & Continuity A key strength of this opportunity is seller continuity. The current owners are willing to stay on post-closing, in either a clinical and/or operational capacity, to ensure: Smooth transition of ownership Retention of staff and patients Continuity of referral and payer relationships Support for a new owner or strategic buyer This flexibility makes the business especially attractive to private equity groups, multi-location operators, and first-time healthcare owners. NDA & Proof of Funds. Offered Exclusively By AcquiTrust Advisors "Your Advantage in Every Acquisition."

$1,700,000
$1,200,000Revenue
$500,000Cash Flow
Profitable Medical & Surgical Supply Business with Foot Center  photo
Medical Practices
+2

Profitable Medical & Surgical Supply Business with Foot Center

Bronx, Bronx County, NY, US

AcquiTrust Exclusive! Step into a fully operational, cash-flowing Durable Medical Equipment (DME) and orthopedic supply enterprise. Successfully serving the New York community for over 15 years, this rare two-location package deal offers immediate scale, established government billing credentials, and a fiercely loyal patient base. 🌟 Investment Highlights: Government-Backed Revenue: Skip the long wait for credentialing! This business comes with active, highly coveted billing relationships with Medicare, Medicaid, and multiple major private insurance providers. Massive Inventory Included: The sale includes all on-hand inventory across both locations, giving you incredible asset value and ensuring a completely seamless, day-one transition. Strategic Dual-Footprint: Located in two high-demand, complementary trade areas—Throggs Neck (Bronx) and Forest Hills (Queens)—capturing a massive and medically active demographic. Diverse & Loyal Client Base: A tenured, multilingual staff (fluent in English, Russian, Spanish, and Arabic) alongside established delivery services have built deep community trust and recurring revenue. 🛒 Premium Products & Services: The company specializes in high-margin, essential medical and orthopedic products, including: Custom orthotic inserts and professional orthopedic footwear fittings Wheelchairs, walkers, and mobility aids Lower extremity braces and support products Incontinence, wound care, and bathroom safety equipment Customized healthcare solutions designed to meet individual patient needs The Opportunity: This is an incredible acquisition for an investor, an existing pharmacy/DME operator looking to expand their footprint, or a medical professional seeking a highly established operation with consistent, insurance-backed demand. Serious inquiries only. Please reach out to sign an NDA and receive the full financial package.

$1,200,000
$704,124Revenue
$165,000Cash Flow
Exclusive Opportunity: Luxury Optical Boutique– Act Fast! photo
Medical Practices
+1

Exclusive Opportunity: Luxury Optical Boutique– Act Fast!

NY, US

Another premier listing from M.O.X. Advisors! If you've ever dreamed of owning a high-end optical business, this is your moment! This fully staffed, turn-key operation in a prime Brooklyn location boasts a loyal client base of 3,000 patients, comprehensive insurance partnerships, and an on-site Doctor of Optometry providing top-tier eye care services. What Makes This a Must-Buy? * Elite Brand Portfolio – Cartier (rare & exclusive!), Tom Ford, Tiffany & Co., Gucci, Oakley, Ray-Ban & more * Profitable & Growing – Sales are skyrocketing! * Top-Tier Equipment & Inventory – Includes $75K in inventory + in-house lens-making lab * Prime Location – Highly desirable Brooklyn area with a fantastic lease * Smooth Ownership Transition – Owner willing to train * Opportunities like this don’t last! Take over a thriving, scalable business with massive growth potential.

$200,000
$777,866Revenue
$150,000Cash Flow

Market Snapshot

National transaction benchmarks for medical practice businesses.

Under $500K

Median revenue$452k
Median cash flow$133k
Median sale price$185k
Multiple range0.9x - 1.9x

$500K to $2M

Median revenue$1.12m
Median cash flow$338k
Median sale price$789k
Multiple range2.2x - 3.2x

Over $2M

Median revenue$3.34m
Median cash flow$918k
Median sale price$4.75m
Multiple range3.3x - 4.7x

A variety of factors can cause businesses to trade outside this range, including earnings quality, operational transferability, key-person risk, growth trajectory, and geography, so a listing priced above or below the typical multiple usually reflects real differences in the underlying business.

What to know about medical practice acquisitions

GW

By George Wellmer

Cofounder & CEO

Key diligence, valuation, financing, and transition considerations for buyers evaluating medical practice acquisitions.

Physician Practices Are Not Like Other Businesses

Acquiring a medical practice involves regulatory, licensing, and structural complexity that does not exist in most other SMB categories. Before engaging in any practice acquisition, retain a healthcare M&A attorney and a CPA with specific healthcare industry experience. Stark Law and Anti-Kickback Statute compliance govern how physicians can be compensated in connection with referrals, and violations carry severe civil and criminal penalties that survive asset purchases under certain conditions. Seemingly straightforward transactions like a retiring physician selling a primary care practice to a new physician buyer can trigger compliance issues that kill deals or expose buyers to inherited liability.

Key-Person Risk Is the Defining Factor

In most medical practice acquisitions, the seller is also the primary revenue generator. Patient relationships, referral networks, and payer contracts are frequently tied to the individual physician, not to the practice entity. Assess honestly what percentage of the practice's revenue is attributable to the selling physician specifically, and what the realistic patient retention rate will be post-sale. Studies consistently show that practices heavily dependent on a single physician experience 20–40% patient attrition following an ownership transition. This needs to be modeled into your purchase price and earn-out structure. A transition period of 6–24 months during which the seller remains in a clinical or consulting role is standard practice for a reason.

Payer Mix Drives Valuation More Than Revenue

Not all revenue is created equal in healthcare. Commercial insurance typically reimburses at rates 89% higher than Medicare. This means two practices with identical revenue can have vastly different earnings quality depending on their payer mix. Request a detailed payer mix report covering the last three years, and analyze trends in commercial vs. government payer composition. Practices with declining commercial payer percentages, driven by aging patient demographics, insurance market changes, or specialty-specific reimbursement pressures, face structural margin compression that current earnings numbers will not yet reflect. Medicaid-heavy practices face additional reimbursement volatility and should be valued conservatively.

Licensing, Credentialing, and DEA Numbers

The acquiring physician must be independently licensed and credentialed with each payer before they can bill for services rendered. This process typically takes 90–180 days depending on payer and specialty and during this window, cash flow can be severely disrupted if not planned for carefully. Request a full list of current payer contracts, credentialing status, and any pending contract negotiations. DEA registration (if applicable to the specialty) must transfer or be re-established. In specialties requiring hospital privileges, the acquiring physician must separately apply for and receive privileges. This process is independent of the practice acquisition timeline and can become a deal-critical path.

Real Estate and Equipment: Own or Lease?

Medical practices frequently occupy real estate owned by the physician-seller or a related entity, with rent paid at above- or below-market rates to the practice. Normalize the rent to fair market value when calculating SDE and determine whether the practice real estate is included in the transaction or subject to a separate negotiated lease. Medical equipment like imaging systems, diagnostic equipment, and EMR infrastructure depreciates quickly and represents significant replacement cost. Request full asset schedules with purchase dates, current book value, and independent FMV assessments for major equipment. EMR system compatibility and data migration costs are frequently underestimated in healthcare acquisitions.

Private Equity and What It Means for Independent Buyers

Private equity has become a meaningful force in physician practice M&A, particularly in high-margin specialties. PE-backed platforms pay elevated multiples because they are building scale through acquiring practices as add-ons and capturing multiple arbitrage at exit. Those multiples often do not reflect the economics available to an individual physician buyer acquiring a single practice. In the SMB channel, independent physician-to-physician sales, practices typically transact at .9x to 4.7x SDE, which reflects the true market for practices without institutional scale. Independent buyers can offer something PE platforms cannot: autonomy, clinical independence, and genuine continuity of care. Understanding which of those things the seller values is often the key to structuring a winning offer.

Frequently Asked Questions

Answers to common buyer questions for this market.

Confidentiality management in medical practice acquisitions is critical. It also gets handled poorly more often than it should. The standard approach: conduct initial due diligence on financials, payer contracts, operational data, amongst others under a mutual NDA before any staff disclosure. The selling physician should be the only person in the practice aware of the transaction until the purchase agreement is signed. Staff disclosure typically happens two to four weeks before closing. Early enough for transition conversations. Not so early that you're creating months of uncertainty and attrition. Premature disclosure is one of the most common causes of pre-closing patient and staff loss. Once staff know a practice is selling, some start exploring other options immediately. That's rational behavior on their part. Your job is to minimize the window between disclosure and close.