Tupelo Data Room

Medical Practice for Sale in Florida

Nationally, similar businesses sell at 0.9x to 4.7x SDE. Compare live listings and connect with sellers.

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Established Chiropractic & Rehab Practice photo
Medical Practices

Established Chiropractic & Rehab Practice

Plantation, Broward County, FL, US

Reason for Sale: Relocating-Established Chiropractic & Rehab Practice. This is a well-established chiropractic and rehabilitation clinic offering a turnkey opportunity with immediate cash flow and strong growth potential. The practice is known for delivering high-quality, patient-centered care and has built a loyal, recurring patient base along with a strong reputation in the community. Services include chiropractic adjustments, therapeutic rehabilitation, and customized wellness treatment plans, supported by steady referrals and a professional online presence. The clinic is fully equipped and designed for efficient operations, allowing a new owner to transition seamlessly. All equipment, furnishings, and systems are in place, minimizing startup time and upfront investment. The business presents clear opportunities for growth through expanded marketing, extended hours, additional providers, or the introduction of complementary services. This opportunity is ideal for a chiropractor seeking ownership, a healthcare group looking to expand. Ownership is willing to support a smooth transition post-closing. With an established foundation and strong upside potential, this is a compelling acquisition opportunity. Seller has reduced operating hours to 15 hrs/week over the past few years to begin transitioning out of South Florida.

$100,000
$199,486Revenue
$68,887Cash Flow
Established Ketamine Infusion Clinic | Tampa, FL Area photo
Medical Practices
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Established Ketamine Infusion Clinic | Tampa, FL Area

Tampa, Hillsborough County, FL, US

Established ketamine infusion clinic operating in the Tampa, FL metropolitan area. The clinic is fully built out with multiple private treatment rooms and dedicated clinical and administrative space, supporting efficient, compliant operations. The practice offers a range of ketamine-based treatment options for depression, PTSD, and Anxiety Disorders. The patient base is largely composed of returning patients and supported by structured treatment protocols and bundled service offerings. The seller is prepared to provide two months of on-site training to ensure a smooth transition.

$450,000
$397,059Revenue
$155,113Cash Flow
Award-Winning Membership Wellness Clinic — Lee County, FL photo
Medical Practices

Award-Winning Membership Wellness Clinic — Lee County, FL

Lee County, FL, US

**This Business is Priced to Sell!** LENDER PRE-QUALIFIED (SBA-ready) Financial Snapshot (FYE 2025) Asking Price: $2,250,000 Revenue: $1,391,862 COGS: $341,857.17 Gross Profit: $1,050,004 (75.4% gross margin) SDE: $592,037 Award-winning, premium direct-pay wellness and functional medicine clinic in Lee County, Florida with rocket-like growth and a model built for recurring cash flow. This practice combines membership-based programs with cash-pay services, collecting at time of service and focusing on long-term patient retention through lab-guided care. This is a perfect opportunity for a licensed qualifier hiring a Nurse Practitioner or Physician's Assistant to run clinicals. Primary programs and services * Medically supervised weight management * Men’s and women’s hormone optimization programs with ongoing monitoring * Concierge-style membership care * IV therapy and nutrient injections * In-clinic blood draws and routine lab testing * Additional wellness add-ons including peptides and device-based service packages Facility and scalability Operates from a professionally designed 2,054 SF medical suite featuring an upscale patient waiting area, four patient rooms, one dedicated lab draw room, provider and nurse offices, and three restrooms. The seller states the current footprint can support at least one additional provider, creating a clear path to expand capacity without relocation. Lease All-in occupancy cost is $5,395.53 per month. Lease renewed February 1, 2026 with two renewal options of 36 months each. Team and transition Staff includes two full-time registered nurses, a full-time administrative assistant, and a part-time bilingual receptionist, with transition support provided by the seller. Transaction and buyer requirements Structured as an asset sale with estimated inventory of $1,500 and estimated FF&E of $37,722. Buyer must be a physician or an independent nurse practitioner, or have an acceptable plan to obtain a licensed qualifier. NDA and proof of funds required before release of the business name, exact location, and full offering details.

$2,250,000
$1,391,862Revenue
-Cash Flow
Profitable Optician Practice for Sale photo
Medical Practices

Profitable Optician Practice for Sale

Miami Gardens, Miami-Dade County, FL, US

Profitable optician practice for sale in Miami Gardens, FL, located inside a busy supermarket retail center with excellent visibility, signage, and parking. The retiring owner offers a turnkey operation that blends essential healthcare with retail fashion, generating consistent revenue from comprehensive eye exams, prescription renewals, fittings, and adjustments supported by modern diagnostic equipment. Retail sales include prescription glasses, designer frames, sunglasses, contact lenses, and accessories for adults and children, creating both recurring revenue and strong seasonal demand. A loyal repeat client base, established supplier relationships, attractive retail displays, and experienced staff have built a trusted community brand that national chains cannot match, making this business recession-resistant and immediately cash-flowing. Growth opportunities include expanding insurance partnerships, building an online presence, adding lines, and leveraging community outreach with schools, senior centers, and local businesses. The model is also highly scalable, with strong potential to replicate in other South Florida communities or expand through mobile exam services. MUST HAVE EXPERIENCE IN INDUSTRY OPTICIAN OR OPTOMETRIST.

$109,000
$276,609Revenue
$57,967Cash Flow

Market Snapshot

National transaction benchmarks for medical practice businesses.

Under $500K

Median revenue$452k
Median cash flow$133k
Median sale price$185k
Multiple range0.9x - 1.9x

$500K to $2M

Median revenue$1.12m
Median cash flow$338k
Median sale price$789k
Multiple range2.2x - 3.2x

Over $2M

Median revenue$3.34m
Median cash flow$918k
Median sale price$4.75m
Multiple range3.3x - 4.7x

Directional only. Small sample may not represent the broader market.

A variety of factors can cause businesses to trade outside this range, including earnings quality, operational transferability, key-person risk, growth trajectory, and geography, so a listing priced above or below the typical multiple usually reflects real differences in the underlying business.

What to know about medical practice acquisitions

GW

By George Wellmer

Cofounder & CEO

Key diligence, valuation, financing, and transition considerations for buyers evaluating medical practice acquisitions.

Physician Practices Are Not Like Other Businesses

Acquiring a medical practice involves regulatory, licensing, and structural complexity that does not exist in most other SMB categories. Before engaging in any practice acquisition, retain a healthcare M&A attorney and a CPA with specific healthcare industry experience. Stark Law and Anti-Kickback Statute compliance govern how physicians can be compensated in connection with referrals, and violations carry severe civil and criminal penalties that survive asset purchases under certain conditions. Seemingly straightforward transactions like a retiring physician selling a primary care practice to a new physician buyer can trigger compliance issues that kill deals or expose buyers to inherited liability.

Key-Person Risk Is the Defining Factor

In most medical practice acquisitions, the seller is also the primary revenue generator. Patient relationships, referral networks, and payer contracts are frequently tied to the individual physician, not to the practice entity. Assess honestly what percentage of the practice's revenue is attributable to the selling physician specifically, and what the realistic patient retention rate will be post-sale. Studies consistently show that practices heavily dependent on a single physician experience 20–40% patient attrition following an ownership transition. This needs to be modeled into your purchase price and earn-out structure. A transition period of 6–24 months during which the seller remains in a clinical or consulting role is standard practice for a reason.

Payer Mix Drives Valuation More Than Revenue

Not all revenue is created equal in healthcare. Commercial insurance typically reimburses at rates 89% higher than Medicare. This means two practices with identical revenue can have vastly different earnings quality depending on their payer mix. Request a detailed payer mix report covering the last three years, and analyze trends in commercial vs. government payer composition. Practices with declining commercial payer percentages, driven by aging patient demographics, insurance market changes, or specialty-specific reimbursement pressures, face structural margin compression that current earnings numbers will not yet reflect. Medicaid-heavy practices face additional reimbursement volatility and should be valued conservatively.

Licensing, Credentialing, and DEA Numbers

The acquiring physician must be independently licensed and credentialed with each payer before they can bill for services rendered. This process typically takes 90–180 days depending on payer and specialty and during this window, cash flow can be severely disrupted if not planned for carefully. Request a full list of current payer contracts, credentialing status, and any pending contract negotiations. DEA registration (if applicable to the specialty) must transfer or be re-established. In specialties requiring hospital privileges, the acquiring physician must separately apply for and receive privileges. This process is independent of the practice acquisition timeline and can become a deal-critical path.

Real Estate and Equipment: Own or Lease?

Medical practices frequently occupy real estate owned by the physician-seller or a related entity, with rent paid at above- or below-market rates to the practice. Normalize the rent to fair market value when calculating SDE and determine whether the practice real estate is included in the transaction or subject to a separate negotiated lease. Medical equipment like imaging systems, diagnostic equipment, and EMR infrastructure depreciates quickly and represents significant replacement cost. Request full asset schedules with purchase dates, current book value, and independent FMV assessments for major equipment. EMR system compatibility and data migration costs are frequently underestimated in healthcare acquisitions.

Private Equity and What It Means for Independent Buyers

Private equity has become a meaningful force in physician practice M&A, particularly in high-margin specialties. PE-backed platforms pay elevated multiples because they are building scale through acquiring practices as add-ons and capturing multiple arbitrage at exit. Those multiples often do not reflect the economics available to an individual physician buyer acquiring a single practice. In the SMB channel, independent physician-to-physician sales, practices typically transact at .9x to 4.7x SDE, which reflects the true market for practices without institutional scale. Independent buyers can offer something PE platforms cannot: autonomy, clinical independence, and genuine continuity of care. Understanding which of those things the seller values is often the key to structuring a winning offer.

Frequently Asked Questions

Answers to common buyer questions for this market.

Confidentiality management in medical practice acquisitions is critical. It also gets handled poorly more often than it should. The standard approach: conduct initial due diligence on financials, payer contracts, operational data, amongst others under a mutual NDA before any staff disclosure. The selling physician should be the only person in the practice aware of the transaction until the purchase agreement is signed. Staff disclosure typically happens two to four weeks before closing. Early enough for transition conversations. Not so early that you're creating months of uncertainty and attrition. Premature disclosure is one of the most common causes of pre-closing patient and staff loss. Once staff know a practice is selling, some start exploring other options immediately. That's rational behavior on their part. Your job is to minimize the window between disclosure and close.